{"id":261501,"date":"2022-03-16T16:04:53","date_gmt":"2022-03-16T20:04:53","guid":{"rendered":"https:\/\/www.oviahealth.com\/?post_type=article&p=261501"},"modified":"2022-03-16T16:06:20","modified_gmt":"2022-03-16T20:06:20","slug":"failed-embryo-transfer","status":"publish","type":"article","link":"https:\/\/www.oviahealth.com\/guide\/261501\/failed-embryo-transfer\/","title":{"rendered":"The ups and downs of the IVF journey"},"content":{"rendered":"\n

If you tried to conceive on your own for a while with no success, you\u2019re likely familiar with the disappointment that follows a negative pregnancy test. Given the high stakes of in vitro fertilization<\/a> (IVF) \u2014 the medications, the physical and emotional side effects, the cost \u2014 finding out you\u2019re not pregnant can hurt a whole lot more than you expected. For some people, a failed transfer feels like a miscarriage because an embryo made it to the uterus, it just didn\u2019t implant.\u00a0<\/p>\n\n\n\n

A failed embryo transfer<\/h2>\n\n\n\n

Although it\u2019s easy to wonder what you did wrong, a failed embryo transfer is not your fault. Most people need more than one embryo transfer to bring home a baby. The good news is, your odds of success are fairly high within six cycles. About 86% of those 35 and under get pregnant within six IVF cycles and about 42% of those over the age of 40. \u201cMost clinics will also offer PGS\/PGD genetic testing, that is generally more meaningful than grading embryos visually in a lab. Higher grade embryos have a statistically higher chance of leading to viable pregnancies,\u201d for example some research shows a 95% success rate with three normal genetically tested embryos. PGS stands for Preimplantation Genetic Screening and can be used to screen for genetic abnormalities, while PGD (or Preimplantation Genetic Diagnosis) is used when one or both parents have family histories of certain issues to search for those specific genetic abnormalities.\u00a0<\/p>\n\n\n\n

Egg quality is the biggest predictor of success. Highly graded, genetically screened normal embryos are the most likely to implant. But even genetically screened normal embryos with good grades can fail to result in pregnancy. There aren\u2019t always clear answers when it comes to why some embryos implant and others don\u2019t.\u00a0<\/p>\n\n\n\n

When you\u2019re ready, you can try again. If you have frozen embryos, you don\u2019t have to do another retrieval, unless you prefer to bank more embryos<\/a>. If you decide to do another retrieval, your doctor may change your medication protocol to see if that changes the quantity and quality of the eggs and embryos.\u00a0<\/p>\n\n\n\n

Additional testing<\/h2>\n\n\n\n

If you\u2019ve had multiple failed embryo transfers, your doctor may want to perform additional tests like a hysteroscopy, which uses a scope to look inside the uterus and rule out any potential uterine issues, like polyps. Uterine masses, like polyps and fibroids, and inflammation, can make it difficult for an embryo to implant, so diagnosing these issues ahead of time is key. Your doctor may also adjust your transfer protocol to see if that leads to a better outcome. For example, they may add more progesterone or have you take a different form of progesterone.\u00a0<\/p>\n\n\n\n

A mental health note <\/h2>\n\n\n\n

Staying busy and preparing for your next transfer can be a helpful distraction, but it\u2019s also important that you take time to process your grief. Find people you can open up to about how you\u2019re feeling, whether that\u2019s a partner, friend, or mental health professional. It may also help to talk to someone who gets what you\u2019re going through. Some fertility clinics offer support groups for their patients. If your clinic doesn\u2019t have a support group, you can ask them to create one, or see if Resolve: The National Infertility Association<\/a> offers a local or virtual support group.\u00a0<\/p>\n\n\n\n

Reviewed by the Ovia Health Clinical Team<\/em><\/p>\n\n\n\n

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